SCALE EFFECTS IN LARGE COASTAL MOBILE BED MODELS

Large-scale Coastal Behaviour in Relation to Coastal Zone Management

Marcel J.F. Stive The development of coastal erosion management addressing typical traditional erosion problems towards coastal zone management addressing the evaluation of alternative solutions to guarantee a variety of coastal zone functions on their economic time scale has necessitated the formulation of large-scale coastal evolution (LSCE) models. Using the coastal evolution of the Netherla...

Estimating Large Scale Scale Signaling Networks through Nested Effects Models from Intervention Effects in Microarray Data

Targeted interventions in combination with the measurement of secondary effects can be used to computationally reverse engineer features of upstream nontranscriptional signaling cascades based on the nested effect structure. We extend previous work by Markowetz et al., who proposed a statistical framework to score hypothetical networks for this purpose. Our extensions go in several directions: ...

Very-large-scale motions in rough-bed open-channel flow

Long-duration particle image velocimetry measurements in rough-bed open-channel flows (OCFs) reveal that the pre-multiplied spectra of the streamwise velocity have a bimodal distribution due to the presence of largeand very-large-scale motions (LSMs and VLSMs, respectively). The existence of VLSMs in boundary layers, pipes and closed channels has been acknowledged for some time, but strong supp...

Large-scale Validation of Counterfactual Learning Methods: A Test-Bed

The ability to perform effective off-policy learning would revolutionize the process of building better interactive systems, such as search engines and recommendation systems for e-commerce, computational advertising and news. Recent approaches for off-policy evaluation and learning in these settings appear promising [1, 2]. With this paper, we provide real-world data and a standardized test-be...

The application of DEA and queuing models to large scale computer networks